Mass. doctor on new, proposed travel restrictions amid COVID-19 delta spread

The European Union is recommending new travel restrictions for American tourists as COVID-19 cases in the U.S. continue to surge. Preeti Mehrotra, MD (Infection Control, BIDMC) discussed the proposed travel restrictions and said international travel plays a role in global transmission.

Booster shot rollout against COVID-19 is likely to differ from the first vaccine effort

Russell Phillips, MD (Internal Medicine, BIDMC) comments on how some primary care doctors are using a state-driven system to order vaccination doses for their patients.

mRNA was supposed to stay ahead of variants. Why aren’t we using its full potential?

Dan Barouch, MD, PhD (Center for Virology and Vaccine Research, BIDMC) said vaccine manufacturers have created shots updated for the Delta variant but that the reason why the Delta variant is able to cause so many breakthrough infections has more to do with its hyper infectiousness rather than its intrinsic ability to evade antibodies.

J&J vaccine booster shot raises antibody levels 9-fold, company says

A new study submitted to medRxiv found that giving a booster dose of the Johnson & Johnson shot six months after primary vaccination results in a nine-fold increase of a crucial antibody response. Dan Barouch, MD, PhD (Center for Virology and Vaccine Research, BIDMC), who helped in the vaccine development with his team but was not involved with this trial, said that boosting after six months appears to be safe, and boosts immune responses substantially.

The State of the pandemic

In this Harvard Magazine feature, Dan Barouch, MD, Ph.D. (Center for Virology and Vaccine Research, BIDMC) is listed amongst three scientists who took stock of the virus’s epidemiology and pathogenesis, the diagnosis and treatment of the disease it causes, and the interplay of variants and vaccines. Barouch helped develop the single-shot Johnson & Johnson vaccine, previously developed vaccines against HIV and Zika, and is actively involved in SARS-CoV-2 vaccine research and assessment.

What to know about boosters if you got the Johnson & Johnson vaccine

Dan Barouch, MD, PhD (Center for Virology and Vaccine Research, BIDMC) discusses data from a clinical trial released earlier this month showing that the Johnson & Johnson vaccine his team helped develop provides substantial protection against the Delta variant.

Cooperation under pressure: Lessons from the COVID-19 swab crisis

In a first-person retrospective and analysis published in the Journal of Clinical Microbiology, Ramy Arnaout, MD, DPhil (Pathology, BIDMC) details the collaborative and open-source effort he coordinated to address the shortage of swabs that hampered the nation’s ability to test for and track the spread of COVID-19 in the early days of the pandemic, and details the lessons learned.

As Virus Cases Surge, Biden Administration Encourages More Use of Antibody Treatments

As Delta variant cases surge around the country, the Biden Administration renewed its call for health providers to use monoclonal antibody treatments. Dan Barouch, MD, PhD (Center for Virology and Vaccine Research, BIDMC) said monoclonal antibody treatments are important tools that have shown substantial therapeutic effects.

FDA permits Covid vaccine booster shots for people with weakened immune systems

In a CDC advisory group meeting in June, Dan Barouch, MD, PhD (Center for Virology and Vaccine Research, BIDMC) said the hardest to vaccinate people are those who are immunosuppressed.