In the midst of the COVID-19 vaccines rollout, clinicians and researchers are working to assess next generation COVID-19 vaccine candidates, and as part of that effort, researchers are presenting alternatives to measure a vaccine’s effectiveness by using immune markers that a person develops in their blood after inoculation. Dan Barouch, MD, PhD (Center for Virology and Vaccine Research, BIDMC) spoke to how trials so far suggest that levels of an antibody called immunoglobulin G (IgG) could serve as that proxy indicator.

As placebo-controlled testing falls out of favour, vaccine developers eye blood markers and challenge trials to assess next-generation candidates.

Nhi Vo (Radiology, BIDMC) looks over a carpet of daffodils left for medical workers at BIDMC by Boston-based floral company Cityscapes. Editor’s note: Photo is featured April 10.

The photos that helped us tell the stories of 2020

Good Morning America: Barouch’s lab studying new, more contagious COVID strains

American lab studying new, more contagious COVID-19...

The Boston Globe’s latest on what people need to know about the vaccine rollout in Massachusetts included Johnson & Johnson’s vaccine development in partnership with BIDMC. Johnson & Johnson expects to have early data from its trial by the end of January, with hopes of submitting an application for FDA emergency use authorization in February.

Five things you need to know about the vaccine rollout in Mass.

As 2021 begins, doctors from Massachusetts hospitals worry infections from holiday gatherings will crowd ICUs even more. David Longworth, MD (President, Lahey Hospital) expressed concern about the impact of the holidays in contributing a surge upon the existing surge.

Infectious Disease Doctors Look Back At A Tough Year — And Forward With Concern

Mary LaSalvia, MD (Infectious Disease, BIDMC) and Kenneth Wener, MD (Infectious Disease, LHMC) joined with other Boston infectious disease experts to address the COVID-19 pandemic and share 2021 resolutions in an opinion piece for the Boston Globe.

As we ring in a new year, here are our resolutions; please consider joining us.

The contagious variant of the coronavirus spreading through Brittan has appeared in Colorado and California, but scientists are still unsure how much more easily the mutant spreads. Dan Barouch, MD, PhD (Center for Virology and Vaccine Research, BIDMC) spoke to the virus replication process and spread.

A more contagious version of the coronavirus may alter the course of the pandemic in the United States, researchers said.

The discovery of a more contagious coronavirus strain in the United States has heightened the urgency to ramp up the national vaccine rollout. Dan Barouch, MD, PhD (Center for Virology and Vaccine Research, BIDMC) said there’s a high chance these variants are already circulating around the United States, and that the data to determine whether this is a problem needs to be generated.

“We need to be in overdrive now,” one pandemic expert said.

Richard Nesto, MD (CMO, BILH) discussed the rollout of vaccines to BILH staff.

Hospitals vaccine rollout starts out rough, but picks up steam